In my case, my Magnepan 1.6 are in the front left/right. My dual TN1220's are on the right wall 1/3 back from the front wall and 2/3 back from the front wall.
Given the subs side wall locations, higher crossover points become noticeable and distracting.
So I would amend my previous reply by saying that cross over points are going to be room and position dependent. But lower cross over points will likely be less problematic.